Cary Roseth, associate professor of educational psychology at Michigan State University, said the study suggests cadaver-based instruction should continue in undergraduate human anatomy, a gateway course to medical school, nursing and other health and medical fields.
In the US, most anatomy courses still emphasise the use of cadavers, although in many cases digital technologies supplement the instruction.
Yet there is a growing debate over whether cadavers are needed at all; some medical schools in Australia and the UK have stopped using cadavers to teach anatomy altogether.
"Our findings indicate that educational technology can enhance anatomy instruction but is unlikely to fully replace cadavers," said Roseth, who co-authored the study.
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The researchers studied a semester-long undergraduate anatomy lecture course with 233 students who were assigned to one of 14 labs.
One group of students learned on a cadaver and was tested on a cadaver. Another group of students learned on a multimedia learning system and also was tested on a cadaver.
On identification, the students who learned on a cadaver scored, on average, about 16 per cent higher than those who learned on the simulated system.
On explanation, the students who learned on a cadaver scored about 11 per cent higher.
This finding was particularly surprising, Roseth said, given that one of the benefits of the multimedia programme is that it can show how parts of the body work - such as blood flow through carotid arteries - while a cadaver cannot.
The difference in the average scores, Roseth noted, was essentially the difference between one grade.