The 20-year-old star sang her 2016 hit "Bad Things" with rapper Machine Gun Kelly, reported Entertainment Tonight.
The duo sported matching white ensembles for their performance, which brought Candance Cameron Bure, JoJo Siwa and more to their feet.
While Cabello rocked her performance, Fifth Harmony also received love during the show, collecting trophies for favorite music group and favourite song- "Work From Home".
The song interestingly features Cabello's vocals, which was recorded before she exited the group.