Sergio Canavero, from the Turin Advanced Neuromodulation Group in Italy, who first proposed the idea in 2013, has published a summary of the technique he believes will allow doctors to transplant a head onto a new body.
The technique, published in the journal Surgical Neurology International, involves cooling the recipient's head and the donor body to extend the time their cells can survive without oxygen.
The tissue around the neck is dissected and the major blood vessels are linked using tiny tubes, before the spinal cords of each person are cut. Cleanly severing the cords is key, said Canavero.
To achieve this, Canavero intends to flush the area with a chemical called polyethylene glycol, and follow up with several hours of injections of the same stuff.
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Just like hot water makes dry spaghetti stick together, polyethylene glycol encourages the fat in cell membranes to mesh, 'New Scientist' reported.
Next, the muscles and blood supply would be sutured and the recipient kept in a coma for three or four weeks to prevent movement.
When the recipient wakes up, Canavero said they would be able to move and feel their face and would speak with the same voice.
He said that physiotherapy would enable the person to walk within a year. Several people have already volunteered to get a new body, he said.
The trickiest part will be getting the spinal cords to fuse. Polyethylene glycol has been shown to prompt the growth of spinal cord nerves in animals, and Canavero intends to use brain-dead organ donors to test the technique.
Canavero plans to announce the project at the annual conference of the American Academy of Neurological and Orthopaedic Surgeons (AANOS) in Annapolis, Maryland, in June.