The internationally renowned scientist, who was at the forefront of HIV research from the very beginning of the global AIDS epidemic, drowned yesterday while swimming off Bal Harbour in Florida, Radio Canada said.
"UNAIDS is deeply saddened by the tragic death of pioneering HIV researcher Mark Wainberg," the agency dedicated to battling the disease said in a statement.
Wainberg and his colleagues identified one of the main anti-retroviral medicines used to treat HIV infection and also contributed to the understanding of HIV drug resistance.
Linda-Gail Bekker, head of the International AIDS Society (IAS), which Wainberg lead from 1998, said the HIV/AIDS research community had "lost one of our fiercest champions".
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"He was the epitome of dedication from the earliest days of the response," she said, adding that "the impact of his work... Will live on through the millions of people accessing HIV treatment and those of us who were lucky enough to know him".
Wainberg, who served as an informal advisor to UNAIDS, was heading AIDS research at the Lady Davis Institute for Medical Research at the Jewish General Hospital and also of McGill University's AIDS Centre in Canada at the time of his death.