The witnesses and security officials say the early Wednesday blast completely destroyed the finance ministry building, damaged nearby houses and triggered fires in shops in the area. They spoke on condition of anonymity, fearing retribution.
The US-based SITE Intelligence Group, which monitors jihadi websites, said the Islamic State group's affiliate in Yemen claimed responsibility in an online statement.
Aden has seen an uptick in violence, with a series of attacks and assassinations claimed by the IS branch. The city is the seat of Yemen's internationally recognized government, which s at war with Shiite rebels.
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