More than 50 people were wounded in the attack in Al-Horra, SANA said, blaming the attack on rebels fighting to overthrow President Bashar al-Assad.
The Islamic Front, a rebel coalition, claimed responsibility. It said on Twitter that a radio-controlled bomb had targeted a "gathering of Assad militia."
The Syrian Observatory for Human Rights said 37 people were killed, including civilians as well as security personnel, and more than 40 wounded.
A car bomb exploded in the city of Homs, to the south of Hama, yesterday killing at least six people in a neighbourhood populated by Alawites, the Islamic sect to which Assad belongs.