The same-sex drama's director Todd Haynes also took home the wilde artist of the year award for his exceptional work besides Blanchett winning the film actress gong.
Leonardo DiCaprio scored film actor of the year for his role in "The Revenant," while Amy Schumer took away the wilde wit of the year honour.
Channing Tatum starrer, "Magic Mike XXL," won the campy flick of the year notch.
"Amy" directed by Asif Kapdia received the documentary of the year award whereas Oscar-nominated Hungarian movie "Son of Saul" won the foreign language film of the year.
Meanwhile in the TV categories, "Transparent" had the most wins with three, including TV Comedy of the Year, LGBTQ Show of the Year, and TV Actor of the Year for Jeffrey Tambor.
Taraji P Henson was named TV Actress of the Year for "Empire".