Chaka, 63, reportedly said she has been battling an addiction to the same medication that led to Prince's death and that his passing had spurred her decision to seek treatment.
Prince died from an overdose of fentanyl, an opioid painkiller at age 57 at his Paisley Park studios in April.
"Chaka Khan has entered an addiction rehabilitation and aftercare program which will cause her to postpone all dates scheduled for the month of July," her rep said in a statement to E! News.
Chaka was good friends with Prince and they collaborated on several occasions.
The singer has cancelled several of her summer tour dates to focus on her health.
It is not for the first time that she has sought help. She had also spent time in rehab for the same issue in 2013.