The late-night chat show will not be returning for a third season, reported The Wrap.
'Hello Ross' premiered on E! last September, and featured Mathews discussing pop culture events with guests such as Kathy Griffin and Brandi Glanville.
Mathews is remaining with the network to become a panelist on 'Live From E!', along with Jason Kennedy and Maria Menounos.
Pop culture roundtable show 'Live From E!' is making the jump from digital to E!'s primetime television lineup.
'Live From E!' will premiere on September 8.