The documents include original manuscripts from "Che's" youthful "Motorcycle Diaries" days, to his diary from the mountains of Bolivia where he was executed by that nation's military in 1967.
They are now recognised as world heritage and will be protected and cared for with the help of the United Nations Educational, Scientific and Cultural Organisation.
The Memory of the World Register comprises nearly 300 documents and collections from five continents. Guevara's works are among 54 new additions this year.
His widow, daughter and son were on hand at a ceremony in Havana today to celebrate the inclusion of the documents in the register.