Jose Mourinho has already seen his side slip up at home in Group G with Klaas Jan Huntelaar punishing the Blues for failing to make more of a number of chances by scoring Schalke's equaliser in the 1-1 draw in the opening game of their latest European campaign.
Chelsea recovered from that disappointment with victory over Sporting in Lisbon.
Saturday's 2-1 victory at Crystal Palace ensured Chelsea will return to European action having maintained their unbeaten start and five-point advantage in the Premier League.
"For Tuesday I cannot make lots of changes because I cannot break the balance of the team," said Mourinho.
"I can make a couple of changes. But I don't think I'm going to have any of the injured players back. I don't think Ramires will be available, Andre Schurrle, Diego Costa for sure is not available."