The University of Toronto study found that men who experienced parental divorce before they turned 18 had 48-per-cent higher odds of ever smoking 100 or more cigarettes than men whose parents did not divorce.
Women from divorced families were also at risk, with 39-per-cent higher odds of smoking in comparison to women from intact families.
"Finding this link between parental divorce and smoking is very disturbing," said lead author Esme Fuller-Thomson, Sandra Rotman Chair at University of Toronto's Factor-Inwentash Faculty of Social Work.
"Each of these characteristics has been shown in other studies to be linked with smoking initiation. However, even when we took all these factors into account, a strong and significant association between parental divorce and smoking remained," Fuller-Thomson said in a statement.
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A total of 1,551 sons and 2,382 daughters had experienced their parents' divorce before the age of 18. A total of 4,316 men and 5,072 women reported that they had smoked at least 100 cigarettes in their life.
From this study, researchers cannot determine why parental divorce is linked to smoking initiation.
However, co-author Joanne Filippelli suggested it is possible that "children upset by their parents' divorce may use smoking as a coping mechanism to regulate emotions and stress".