Drug addicts who have not recovered from addiction must apply to have their driver's licenses revoked within 30 days.
Authorities will revoke the licenses of those who fail to do so in accordance with relevant regulations, the Ministry of Public Security said in a circular.
Under the new rule, police will not accept driver's license applications filed by drug addicts, and this decision will be made based on the official list of registered drug addicts, state-run Xinhua news agency reported quoting the circular.
In addition, the ministry ordered local police to intensify roadside checks and carry out such checks on a regular basis.
Those found to have been driving under the influence of drugs will be punished or fined, and those who are found to be drug addicts will be stripped of their driver's licenses, the circular added.
The circular marks China's latest efforts to curb the incidences of driving under the influence of drugs, as the country has seen an increasing number of such traffic accidents.
Fourteen people died in east China on April 22 in one of the most fatal drug-related traffic accidents.