China took six of the top 10 slots in a study of schools there and in Brazil, Russia, India and South Africa by the London-based rankings firm QS.
The report placed Tsinghua and Peking University, both in Beijing, in first and second place, and said China was "the most likely of the BRICS nations to achieve its goal of developing world-class universities".
Brazilian institutions took two of the top 10 spots, with Russia and South Africa on one each.
"The key question for China is whether this massive output of research papers will turn in time into influential discoveries cited around the world. It seems from these results that China's top universities are managing this feat, but it may be harder to replicate across the system as a whole," QS said.
Also Read
It also noted that in its overall world rankings, Tsinghua trails in 48th place, and said "the BRICS countries are still a long way from competing with the elite higher education systems of Europe, Australia, the US, Singapore or Hong Kong".
Late last year Peking University fired outspoken economics professor Xia Yeliang after 13 years, citing poor teaching.
Chinese universities accounted for 71 of the total 200 entities ranked by QS, followed by Russia with 53.
QS measured schools by eight factors, primarily academic reputation which was weighted at 30 per cent, employer reputation and faculty-to-student ratio each at 20 per cent, followed by "staff with a PhD" and "papers per faculty" at 10 per cent each.
It determined academic reputation based on a "major global survey of academics, who are asked to identify the top-performing universities in their own field".
"The Indian university system is a strong on a national scale, but our data shows that it holds little attraction for globally mobile students and academics," QS said.