Chinese remain divided over the founder of the People's Republic, with many nostalgic towards his 27-year-rule and others insisting his policies led to the deaths of millions.
The anniversary, which falls on Thursday, has particular significance this year and authorities in Mao's hometown have reportedly spent billions, even as President Xi Jinping called for "simple" celebrations.
"The anniversary is a big date for Chinese people," said Shen Yang, a 48-year-old businessman who will travel to Shaoshan in Hunan province, where Mao spent some of his formative years.
"I believe that the new China created by Mao was great, and that's why we should celebrate and believe in him."
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For others, Mao -- who in 1949 led the Communist party to victory in a brutal civil war and died in 1976 -- is remembered as a tyrant who led disastrous political campaigns that killed tens of millions.
He consolidated his power in the 1950s with brutal purges of opponents, while estimates say more than a million people were slaughtered in a movement to redistribute rural land to China's peasants.
Next came the 1966 to 1976 "Cultural Revolution," seen as an effort by Mao to eliminate political enemies, leading to violence that one account estimates caused half a million deaths in 1967 alone.
But there has never been a full historical reckoning of his actions in China, where the ruling party censors accounts of his rule that highlight brutality and challenge the official line.
"Mao's biggest sin is that he interrupted China's progress towards constitutionalism and democracy," Beijing-based historian Zhang Lifan wrote in an online commentary on the anniversary.
But the Communist party "continues to use Mao as a sort of father figure for the revolution", said Kirk Denton, of Ohio State University.