"China holds a consistent and clear stance on the anti- missile issue," Chinese Foreign Ministry spokesperson Hua Chunying said.
Hua said China is "deeply concerned" over the decision by the United States and the Republic of Korea (ROK) to launch an official negotiation on the deployment of an advanced US missile defense system, called Terminal High Altitude Area Defense (THAAD), on the Korean Peninsula.
THAAD system is a sophisticated US-developed one aimed at defending major population centres and key infrastructures from enemy short and medium-range missile attack.
She said moves to advance the deployment will escalate tensions on the peninsula, which will do harm to regional peace and stability, and set back efforts to address the current situation.
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"We demand the countries concerned be prudent when handling the issue," Hua added.
Earlier, Hua had "expressed regret" over North Korea's launch of a long-range rocket, after Pyongyang said it successfully put a satellite into orbit.
"With regards to the DPRK's insistence on implementing a launch of missile technology in the face of international opposition, China expresses regret," Hua said.