The low-intensity explosive, rigged to a motorbike and exploded with the help of a remote control device, injured a truck driver in Rohri area of Sukkur district of Sindh province.
"Unknown accused attacked a Chinese engineer's vehicle near Rohri but he was unhurt," police official Masood Mahar said.
He said the truck driver received minor injuries in the blast.
He said the Chinese engineer was being escorted by paramilitary Rangers when the explosion occurred.
More From This Section
No one has claimed responsibility for the attack but Taliban militants in the past had been targeting foreigners, especially Chinese nationals working in Pakistan.
Several Chinese workers and engineers are working in Pakistan in various schemes being implemented under the China- Pakistan Economic Corridor (CEPC) project.
The ambitious CPEC project was launched in early 2015 to link China's remote Xinjiang region with the Arabian Sea through Pakistan by building a network of roads, railways, energy parks and industrial zones.
The attack on the Chinese engineer came on a day when Prime Minister Nawaz Sharif inaugurated a 448-kilometre-long Sorab-Hoshab road, an important segment of western route of the CPEC in the restive Balochistan province.
The road network in Balochistan would connect Gwadar port up to Khunjerab border with China and would ensure economic activity, reduce poverty and unemployment in the province, Sharif was quoted as saying by the media.