Xi will set the tone of his visit in meetings and a keynote speech to leaders of states such as Washington that do substantial business with China, as well as the heads of top companies with huge China interests such as Boeing and Microsoft.
With the Obama administration increasingly at odds with Beijing over its territorial claims in the South China Sea, cyber theft of US business secrets and alleged discriminatory business practices against US investors in China, Xi could have his best chance to clear some air while in Seattle.
In an interview published Tuesday in the Wall Street Journal, Xi depicted China and the United States leading the world shoulder-to-shoulder, with both common and competing interests.
"Together, China and the United States account for one-third of the world economy, one-fourth of the global population, and one-fifth of global trade," he said.
"If two big countries like ours do not cooperate with each other, just imagine what will happen to the world.