The 32-year-old singer split from Rap-a-Lot Records CEO earlier this month and moved her belongings out of the couple's house, reported Us magazine.
Hours before their breakup became public, Milian tweeted, "I need a cocktail right now." Prince, meanwhile, posted an inspirational quote via Instagram. "Keep Calm, Pray and Leave It All in God's Hands," the text in the picture read.
Prince also commented on the picture, writing, "All one can do!"
Milian and Prince reportedly started dating in 2010, just months after the former divorced The-Dream, with whom she has a four-year-old daughter, Violet.