"I debated him for four and a half hours. I do not even think about responding to him anymore," Clinton, 68, told reporters travelling with her in Pennsylvania.
"So he can say whatever he wants to. He can run his campaign the way he wants to. He can go off on tangents, he can go to Gettysburg and say he is gonna sue women you have made accusations against him," she said.
Clinton, who is leading in polls, claimed that she won the third presidential debate by defeating Trump, 70.
"Well, I will tell you that was the third and last time I will ever have to debate Donald Trump. I mean, think about this. I have now spent four and a half hours on stage with Donald, proving once again I have the stamina to be president and commander-in-chief," she told her supporters in Pittsburg.
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The former first lady called Trump's recent refusal to commit to accept the results of the election unacceptable, saying "We know in our country the difference between leadership and dictatorship, right? The peaceful transition of power is one of those things that sets us apart. And whether you support me or you support my opponent, together we must show that we support American democracy".
Kaine also reflected on why Clinton's historic candidacy resonates with him personally, saying "I would not have gotten very far - in fact, I would not have gotten into my first office -without a whole lot of really amazing women who have lent me their strength along the way sothat I could be the candidate... That is why I am just so proud to be a strong man supporting a strong woman who will be the next president of the US".