Fighting for every single vote at stake, Democratic nominee Clinton and her Republican rival Trump made their last minute forceful argument before the American people with their own vision for the world's largest economy.
Clinton, 69, was joined by husband Bill as she addressed a massive rally in Raleigh in the key battle ground state of North Carolina, which was entertained by Lady Gaga.
The two rallies ended around 1AM (local time), just six hours before opening of the polling booths in the East Coast.
An estimated 200 million people are eligible to cast their votes to elect the country's 45th president along with hundreds of Congressmen and members of state legislatures and local civic bodies.
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More than 42 million have already voted using the "early voting" provision of the American electoral system.
Clinton and Trump crisscrossed several stops in key battleground states on the final day of campaigning which the US media has termed as the "ugliest" and the most divisive till date.
"None of us, none of us, want to wake up on Wednesday morning and wish we had done more," she said, which she repeated in her other election rallies including the one in Philadelphia, which was also addressed by US President Barack Obama and First Lady Michelle.
"Because I do believe we are stronger together; and you voted for an America where we build bridges, not walls; and, maybe most importantly, you voted in great numbers to demonstrate conclusively, once and for all, that, yes, love trumps hate. Let's get out and vote," Clinton said.
"Political establishment has brought distraction of
factories and jobs," Trump said.
"Tomorrow the working class will strike back," he said in New Hampshire and in Michigan he declared "today is the Independence Day".
Trump kicked off his Monday engagements with a rally in Florida.
The Republican presidential nominee would be spending the election day in New York.
His 'victory rally' has been schedule at a hotel in New York, a few kilometres away from the 'victory rally' of Clinton.
This year, the Republican field began with a long list of 17 candidates, including Indian-origin Louisiana governor Bobby Jindal, New Jersey Governor Chris Christie and former Florida governor Jeb Bush. The Democratic field, on the other hand, was not as crowded, with just Hillary Clinton and Senator Bernie Sanders in the race.
Unlike India, in the US campaigning can be done even as voting continues.
Every state would start counting the votes as polling concludes.
One of the main highlight of the last few weeks has been the electioneering blitz by Obama.
In the last phase of the campaign, the Clinton campaign also brought in popular singers, which Trump alleged was a move to attract crowd.
The two campaigns have different theme. While 'Make America Great Again' is the theme of Trump, 'Stronger Together' is Clinton's slogan.
Both the candidates have said they would accept the results of the elections, but reserve the right to challenge in case of close results. The new president would be sworn in on January 20.
Till then the winner of the November 8 general election would be called president-elect and would have a transition team in place working from Washington DC.
Clinton registered her first 'win' in the 2016 elections by four votes to two against her Republican rival Donald Trump soon after midnight in the remote northeastern part of the US.
Voters also cast ballots early today in two other small New Hampshire communities, Hart's Location and Millsfield.