The world's largest beverage maker has been under pressure to grow as people around the world drink less soda, including its flagship Coke.
In October, the Atlanta company reported in October that its third-quarter profit fell 28 percent. Last year it rolled out a pricy milk drink called Fairlife that it says has more protein and less sugar than regular milk. The company also makes Sprite, Fanta and Dasani water.
Quincey, who was named president and chief operation officer last year, will take over as CEO on May 1. The 51-year-old has been with the beverage maker for about 20 years.
Billionaire investor Warren Buffett, whose holding company Berkshire Hathaway Inc. Is Coca-Cola's largest shareholder, said he was pleased with the succession plans.
"I know James and like him," Buffett said in a statement, "and believe the company has made a smart investment in its future with his selection."
Shares of The Coca-Cola Co. Rose 83 cents, or 2 percent, to USD 41.83 in morning trading today. Its stock is down about 5 percent so far this year.