The drug was sent through Aizawl Post Office and it was seized at Rangvamual area near Aizawl on Saturday night over a tip off, a senior official of the Excise and Narcotics department said.
The cocaine was sent by mail from Colombia to a person at Rangvamual most likely to be shipped outside Mizoram, he said.
The Narcotics Control Bureau (NCB) officials were, however, tight-lipped about the seizure.
"We do not know the local rate of the cocaine as we have never seized it before in the state," they said.