Tyrone Simmons, aka Young Caliber, filed papers against 50 and the song's producer William Stanberry in 2010, claiming they had infringed on his rights to use the instrumental for "I Get Money", reported Billboard.
Simmons also named Universal Music Group, Interscope Records and Aftermath Entertainment as defendants.
Officials at the US Court of Appeals for the Second Circuit ruled the case was "time-barred" adding Simmons had waited too long to file the suit, according to Jackson's lawyer, David Leichtman.
"Today the Second Circuit Court of Appeals vindicated Curtis Jackson, aka 50 Cent, in a copyright case relating to his 2007 hit record I Get Money.