Amy Lindsay, who has acted in multiple adult films such as Erotic Confessions, Carnal Wishes, Secrets of a Chambermaid and Insatiable Desires, had appeared in the Cruz campaign advert decrying Rubio as nothing more than a "pretty face."
Cruz said the mistake happened unknowingly. "It happened that one of the actresses who was there had a more colourful film history than we were aware," he told reporters.
"We would not have cast her had we known of that history."
"I have no ill will towards Ted Cruz right now. He's got a job to do," Lindsay told CNN's Jake Tapper on 'The Lead.' "And I'm a middle-class working girl and I had a job to do."
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Cruz, who won the Republican Iowa Caucus early this month, is currently placed behind frontrunner Donald Trump in both national and South Carolina polls. The primary in South Carolina is scheduled for February 20.
Lindsay said she still plans to vote for Cruz.
"Like I said, when I did the ad and the words that came out of my mouth... I was speaking from the heart about some of the issues that I think are true problems in this country that we as Americans are facing today," she said.
Meanwhile, Trump yesterday began airing a new ad in South Carolina focused on illegal immigration featuring Jamiel Shaw, whose son was brutally murdered by an illegal immigrant.
"It is a massive problem in our country and now everybody agrees with me - bad for crime and the economy," he said.
Shaw said: "Donald Trump is the only person fighting to put American families first. He will protect our children and put an end to these senseless acts of violence that are caused by our failed policies and broken immigration system."
"Without strong borders we don't have a country... Donald Trump is a man who stands for what is right. He stands for America and I stand with him," Shaw said.
At the same time, Trump alleged that it was his Republican opponents who were running a negative campaign.
"You see the negative ads now, all phony ads. Those are paid for by lobbyists that are all supporting them," he said.