Betting on his anti-euro, anti-migrant and anti- corruption ticket, ANO (Yes) movement chief Andrej Babis topped opinion polls ahead of the ballot that ends tomorrow afternoon.
"For the first time, the majority will go to parties protesting in one way or another against the functioning of liberal democracy as we know it," the leading Hospodarske Noviny daily said in a Friday editorial.
"These elections are a turning point in the country's journey, both for its internal functioning and its anchoring in the European Union," said the daily, but added that "Czech democracy is not directly endangered, but it has undoubtedly reached a critical point."
Despite being indicted for fraud, Babis has captured around 25-30 per cent voter support in recent polls.
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This puts ANO miles ahead of its current coalition partner, the left-wing Social Democrats, who scored just 12.5 per cent in a recent Median agency poll.
"The dissatisfaction with the traditional establishment has deepened," independent analyst Jiri Pehe told AFP.
"It's an interesting paradox, because the country has been exceptionally successful in the past few years, and still voters are upset with the parties that take credit for this," he added.
With unemployment at 3.8 per cent in September, the lowest level since 1998, the Czech economy is expected to grow by 3.6 per cent this year, according to the central bank.
"We are standing against the traditional parties and we would like to get the chance to show them that the government can be managed in a different way than what our citizens are used to," Babis told AFP yesterday.
The 63-year-old Slovak-born chemicals, food and media tycoon appeared certain to win despite a host of scandals including an indictment over alleged EU subsidy fraud, and suspicions he was a Communist police agent in former Czechoslovakia.
"I'll vote for Babis, because he is accomplished and he means well," Milota told AFP in the capital today, adding that he thought "others conspire against him (Babis) - they blame him for many things only to grab power themselves."
"I expect the election to end up with a rather difficult post-vote situation, maybe even chaos, because Andrej Babis's results won't be as glamorous as expected," said Pehe.
"The recent scandals have had an impact on him after all," he said, adding that he "can see signs of great instability."
Foreign Minister Lubomir Zaoralek, the Social Democrats leader, has downplayed his party's poor showing in the polls, telling AFP yesterday that he was still hopeful to "form the government."
The Median poll showed the Communists could win 10.5 per cent, ahead of two anti-system parties - the Freedom and Free Democracy with 9.5 per cent and the anti-establishment Pirates party with 8.5 per cent.