Czech Education Ministry says Prime Minister Petr Necas and President Barack Obama agreed on the project during their talks at the White House in 2011.
The ministry says it will sign a memorandum of understanding on Wednesday with representatives of US Department of Energy and the US State Department.
The ministry said today the center will be based at the Czech Technical University in Prague and that scientists from four US universities, two laboratories and US Nuclear Regulatory Commission will participate in its programs.