The rock icon joins an extensive list of stars from music and movies who will appear at the Oscars ceremony in Los Angeles on February 28, reported Rolling Stone magazine.
The full list of stars presenting awards or performing includes actors Russell Crowe, Sacha Baron Cohen, Ryan Gosling, Charlize Theron, Eddie Redmayne, and Reese Witherspoon, and the musicians who will take to the stage at the city's Dolby Theatre include Lady Gaga, The Weeknd, Quincy Jones, and John Legend.
Grohl, 47, who made his directorial debut in 2013 with the documentary "Sound City", has been billed as giving a "special performance".
"This year's show reflects a commitment to showcase cinematic contributions from a variety of genres and this latest list of presenters reflects just that.