The actor will be joined by Schwartz in the movie, which is Matt Ratner's directorial debut, according to The Hollywood Reporter.
The film chronicles the story about an unlikely friendship between a struggling stand-up comedian from LA, played by Schwartz, who is forced to return home to Eastern Long Island, and a charismatic, alcoholic dermatologist portrayed by Crystal.
While Castaneda will play the role of Ruis, the amiable security guard who aspires to be a police officer boyfriend of Schwartz's onscreen sister.
The shooting begins in New York this month.