The 38-year-old star has been cast as Krall, one of the evil wizard, Grindelwald's henchmen, reported DigitalSpy.
Actor Johnny Depp will essay Grindlewald in the David Yates-directed film.
Sakurai was most recently seen in Marvel's "Iron Fist" on Netflix as the sickle-swinging assassin Scythe.
He was also a recurring player on the streaming giant's Nordic gangster dramedy "Lilyhammer".
Author J K Rowling finished the script of the yet-to-be- titled second installment of "Fantastic Beasts" in May.
Actor Jude Law has been cast to play a young Albus Dumbledore, while Callum Turner will play Newt Scamander's (Eddie Redmayne) older brother, Theseus.