His 70-year old son Syedna Mufaddal Saifuddin has succeeded him, it was announced here.
Syedna Burhanuddin died this morning at his residence in South Mumbai, a spokesperson for the community said.
"The 52nd Dai al-Mutlaq of the worldwide Dawoodi Bohra community, His Holiness Dr Syedna Mohammed Burhanuddin expired today at the age of 102 at his Mumbai residence at Saifee Mahal," he said.
"Born in Surat, he was the leader of the Dawoodi Bohra community after succeeding his father Syedna Taher Saifuddin in 1965. Under his leadership, the community has achieved remarkable social, economic and educational success across the world.
He was honoured with highest civilian titles like the Star of Jordan and Order of the Nile by the respective governments of Jordan and Egypt. Syedna was conferred Honourary Doctorates for his efforts in social and educational development by renowned institutes like Al-Azhar University, Cairo, Aligarh Muslim University and University of Karachi.
In Mumbai, the one of its kind Raudat Tahera mausoleum which has the entire Quran inscribed in letters of gold and bejewelled with precious stones; the world class Saifee Hospital; and the on-going ambitious Saifee Burhani Upliftment project of the redevelopment of Bhendi Bazaar are some of the major initiatives of Syedna in the city.