Nearly 130 million hectares of forest - an area almost equivalent in size to South Africa - have been lost since 1990, according to a recent report by the Food and Agriculture Organisation of the United Nations (UN).
Deforestation is not a natural phenomenon, but rather results predominantly from human activities, or anthropogenically, researchers said.
Researchers from Lehigh University in the US found that deforestation can impact malaria prevalence by several mechanisms, including increasing the amount of sunlight and standing water in some areas.
"Human-induced changes to the natural environment can have a powerful impact on malaria rates," said Kelly Austin from Lehigh University.
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Researchers build upon evidence that patterns in climate change, deforestation, and other human-induced changes to the natural environment are amplifying malaria transmission.
They used an analytic research strategy that allowed them to look at the causes of deforestation, in order to have a broader focus on the upstream or human-induced causes of land-use change that impact malaria vulnerabilities.
Deforestation from agriculture comes in part from food that is exported to more-developed countries, researchers said.
"In this way, consumption habits in countries like the US can be linked to malaria rates in developing nations," Austin said.
The study was published in the journal AIMS Environmental Science.