Lovato, 24, also brought a special advanced screening of her upcoming animated movie "Smurfs: The Lost Village" for the young patients.
Children gathered to watch the film and their faces lit up when Lovato's character from the film, Smurfette, walked into the room.
CHLA thanked the "Let It Go" hitmkaer via its official Twitter handle by posting, "Smurfette ventured out of The Smurfs village to find out she wasn't alone--She found the kids at CHLA! She also brought along the #SmurfsMovie and the voice of her character, Demi Lovato.