"The untimely break-up between the JD(U) and the BJP has exposed their unholy alliance...It is a divorce of love marriage between two mismatching partners," Prasad told reporters.
The RJD chief said Sharad Yadav and Nitish Kumar have "committed sati" in favour of BJP leader L K Advani, whom he described as a "discarded leader".
"When Advani was sidelined by RSS in favour of Narendra Modi, he played this card and asked JD(U) to threaten NDA coalition," he said.
"Why did you not resign in 2002 after riots like Ramvilas Paswan did?" he asked referring to Kumar.
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The RJD President attributed the break-up in the NDA to "arrogance" of Nitish Kumar.
He said that people of the state would teach a lesson to both the parties in the 2014 Parliamentary elections and also in Assembly polls in 2015.
"The Maharajganj by-poll result is enough indication of things to come in Bihar politics," he said.