Addressing a public meeting here to protest against the suspension of 79 party MLAs, including his son and Opposition Leader M K Stalin from the Assembly last week, he said DMK had in the past overcome many such challenges in its growth.
"DMK has not feared any challenge, (especially) that of the ruling party or the police. It has grown despite all these (factors) and will continue to grow," he said.
Youths, students and women will take it forward, he added.
Karunanidhi, whose party had lost the May 2016 Assembly polls to archrival AIADMK for a second time after 2011, said Dravidian veteran and DMK founder C N Annadurai himself had lost an election but he was never forgotten by the people.
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Earlier, Stalin in his speech said that the DMK has got an "unprecedented" 89 MLAs' strength in the opposition.
proposed by the Centre.
He rued that even senior AIADMK members made unwarranted remarks against Karunanidhi in the Assembly.
Stalin said the Treasury benches often ridiculed his pre-election state-wide tour 'Namakku Name'.
One such remark by an AIADMK member had last week prompted heated exchange of words between the archrivals in the House, culminating in the en masse eviction and suspension of 79 DMK MLAs for a week.
Karunanidhi had last week asked party cadre to organise public meetings across the state to inform the people about "what is happening" in the Assembly.