"Donald Trump just became the Republican nominee. Chip in now to make sure he never steps foot in the Oval Office," Clinton, the Democratic party's presumptive presidential candidate tweeted soon after the 70-year-old real estate mogul's nomination at the Republican National Convention in Cleavland, Ohio.
The Oval Office is the official office of the US President. It is located in the West Wing of the White House Complex.
The focus of the convention on the second day was supposed to be on the economy, but it was Clinton, the former secretary of state, who was in the spotlight.
New Jersey Governor Chris Christie, shaking off the disappointment of being passed over as Trump's running mate, led the coordinated attack on Clinton at the Quicken Loans Arena in Cleavland.
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He performed a show trial of 68-year-old Clinton, whipping the crowd into frenzied chants of "Lock her Up! Lock her up!"
"Is she guilty or not guilty?" Christie asked after every charge he laid before the crowd.
The delegates responded with a resounding: "Guilty!"
"We don't disqualify Hillary Clinton to be the president of the United States," Christie said. "The facts of her life and career disqualify her."
Michael Mukasey, a former attorney general under former
president George W. Bush, was also roped in to attack Clinton.
He said Clinton lied about her motivations in setting up a private email server while secretary of state and said that disqualified her from being US President.
"Hillary Clinton is asking the people of this country and the people of the United States to make her the first President in history to take the oath of office after already having violated it," he said.
The message, Mukasey said, the convention should send to her should be "loud, clear and short: No way, Hillary. No way on earth."