Police made dozens of arrests shortly before midnight when people ignored orders to disperse.
More protests were expected starting today morning, with demonstrators planning to gather downtown.
A judge ruled Friday that Jason Stockley, a 36-year-old who left the department and moved to Houston three years ago, was not guilty in the 2011 death of Anthony Lamar Smith. The ruling set off raucous protests throughout the weekend.
Yesterday's protest began at the police headquarters downtown. Following the same pattern of the previous days, well over 1,000 people marched peacefully for several hours.
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By nightfall, most had gone home. The 100 or so demonstrators who remained grew increasingly agitated as they marched toward the core of downtown. Along the way, they knocked over planters, broke windows at a few shops and hotels, and scattered plastic chairs at an outdoor venue.
Soon after, buses brought in additional officers in riot gear, and police continued to search downtown deep into the night, making arrests shortly before midnight when people ignored orders to disperse.
Later, officers in riot gear gathered alongside a city boulevard chanting "whose street, our street," a common refrain used by the protesters, after successfully clearing the street of demonstrators and onlookers.
Protest organisers said they were frustrated that a few people who have caused trouble at night could make it harder to spread their nonviolent message.