Drake, real name Aubrey Graham, recently teamed up with the 'Baby' hitmaker on his new album Believe, and they played the track for more than 60,000 fans, reported Daily Star online.
"I'll tell you, there's very few people I met in the world that are as talented and as incredible as this young man right here. I want to thank (Bieber) for letting me live a childhood dream, which is my first opportunity to perform at the SkyDome. So thank you, my man," Drake said.
The pair also sang a rendition of Drake's song 'The Motto', with the 18-year-old filling in for Lil Wayne.