The 29-year-old rapper, whose real name is Aubrey Drake Graham, walked away with a total of five awards including the video of the year award for the "Hotline Bling" visuals, which also earned him the best hip-hop video and most buzzworthy Canadian trophies. He led the nominees with seven nods.
Apart from this, Drake also took home the best muchFACT video award for his contribution to Majid Jordan's "My Love".
Director X, who helmed the "Hotline Bling" video took home the best director title.
Cabello took away two more awards as part of band Fifth Harmony. They won the fan fave international artist or group prize and the most buzzworthy international artist or group title for their track "Work from Home".
Justin Bieber and The Weeknd also made it to the winner's list with fan fave artist or group and Canadian single of the Year respectively.
Macklemore and Nick Jonas were among international superstars, who won awards at the event hosted by Gigi Hadid.