The 38-year-old actress posted a picture of hers on the website, reported E!Online.
In the snapshot the blond beauty, who is married to Will Kopelman, poses with open arms in front of a floral-adorned shed.
"My husband had me stop here & take a pic! Athens, flowerland, flower beauty," she captioned the picture.
Fans got excited when Barrymore joined Twitter last week.
Her first tweet was, "Late to the party, but happy to be here! 140 characters should keep me from rambling. Someone told me it doesn't all have to fit in 1 tweet.