Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have conducted a study on 59,000 women in collaboration with the Norwegian Institute of Public Health.
Expectant mothers who consume caffeine, usually by drinking coffee, are more likely to have babies with lower birth weight than anticipated, given their gestational age, the study found.
"The correlation between intake of caffeine and foetal growth was established even among women who followed the official recommendation that they limit caffeine consumption to 200 milligrammes a day (two cups of coffee)," researcher Verena Sengpiel said.
The new results are consistent with previous international studies but are based on a considerably larger cohort.
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The participants were healthy and had uncomplicated pregnancies until delivery, while the results were adjusted for age, smoking, body mass index, nicotine consumption, alcohol use and other variables that affect foetal growth.
"We need to stress that our study did not examine whether caffeine is the specific mechanism substance responsible for the foetus being at greater risk of low birth weight," Sengpiel said in a statement.
The other purpose of the study was to determine whether women who consumed caffeine during pregnancy were more likely to give birth prematurely. Such a correlation could not be established.
The study is published in journal BMC Medicine.