The 26-year-old singer missed his lines while singing his new track "What Do I Know" from his latest album "Divide", reported AceShowbiz.
But, the singer laughed off his mistake and bravely carried on with the song.
Fans took to Twitter to praise the "Shape of You" hitmaker's performance.
"Wow brilliant. Had me in tears," one fan tweeted.
"I think I just fell in love with @edsheeran a little more after that," another user wrote.