Harsch died Friday morning but no information was available about the cause of his death, reported Billboard.
The keyboard player, who was a member of brothers Chris and Rich Robinson's band from 1991 to 2006, also performed with The Detroit Cobras.
A tribute to Harsch was posted on the Facebook page for the Magpie Salute, the band formed by former Crowes guitarist Rich Robinson that featured the keyboardist.
"It is with the saddest of hearts that we bid farewell to our dear friend Eddie Harsch. Eddie was a brilliant musician, with a beautiful heart. We should remember Eddie for his music, his great sense of humor, and his positive outlook on life.
Prior to his death Harsch was preparing for shows with Robinson's band.
The musician, who was born May 27, 1957, in Toronto, Ontario, also performed with the jam band Bulldog.
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