The alert issued by the US embassy in Cairo yesterday was cited in Canadian and Australian travel warnings, with the British Foreign Office later putting out a message that copied the US warning.
Embassy officials declined to comment, and an Egyptian interior ministry official said he was unaware of any specific threat.
"The US Embassy strongly advises US citizens to avoid large gatherings and public spaces such as concert halls, movie theatres, museums, shopping malls, and sports venues in Cairo through Sunday, October 9, due to potential security concerns," it said on its website.
"When contacted to clarify the reasons for issuing the security message, the US embassy denied the presence of any particular reasons or security threats that triggered the alert," he said in a statement overnight.
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He added that the embassy said it was a routine warning over long weekends.
The embassy will be closed on Sunday, a workday in Egypt, for Columbus Day.
"The Foreign Ministry deplored, during the call (with the US embassy), these unnecessary alerts that can have negative impacts, particularly on the economic front," he said.
Egypt has been battered by militant attacks since the army toppled the divisive Islamist president Mohamed Morsi in 2013.
The Islamic State group's branch in Egypt has killed hundreds of policemen and soldiers in attacks, mostly in the restive Sinai Peninsula.
It also claimed responsibility for bombing a Russian airliner carrying holidaymakers from a Sinai resort last year, killing all 224 people on board.
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