One police official suggested action against the sit-in protests by supporters of ousted President Mohammed Morsi could begin as early as daybreak tomorrow.
Officials, who spoke anonymously in line with regulations, told The Associated Press they are also preparing for possible clashes that might erupt in reaction to the cordons they will set up barring anyone from entering.
Morsi's supporters have said they will not leave the sit-ins until the president, ousted in a popularly supported coup July 3, is reinstated.
Egypt's new leadership says that the sit-ins and protests have frightened residents of Cairo, sparked deadly violence and disrupted traffic in the capital. Leaders of the sit-in say their protests have been peaceful and blame security forces and "thugs" for violence.
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The Arab world's most populous country is readying itself for more potential bloodshed. Already more than 250 people have killed in violence since Morsi's ouster.
The Interior Ministry had said earlier it would not clamp down on the protesters but will take gradual measures, which include the cordons. Other measures suggested include the use of water cannons and tear gas to minimize casualties.
The protesters, expecting an imminent security push to clear them out, have begun fortifying their positions.