The assembly, elected in November and December, is also the first elected chamber since el-Sissi, as military chief, led the ouster of President Mohammed Morsi in 2013 following massive protests against the Islamist leader and his Muslim Brotherhood.
Today's session is mostly a procedural one, with lawmakers taking the oath in turn. The chamber is also expected to elect a speaker and two deputies.
The last parliament was dominated by Islamists and dissolved by a court ruling in 2012.
The new chamber's first task will be to ratify some 300 presidential decrees issued by el-Sissi since taking office in June 2014 and interim president Adly Mansour before him.