The plane, an Airbus A-330-220, landed at the airport in the town of Urgench, about 840 kilometres west of the Uzbek capital, Tashkent, three hours after it took off from Cairo at around 11:30 p.M. Yesterday.
All 135 passengers and crew on board were evacuated and the aircraft was being searched, the officials said. They had no word on whether a bomb or any other suspicious object was found on board.
In Russia, the news agency RIA Novosti quoted an unnamed official with Uzbekistan Airways as saying the airport has been closed following the EgyptAir plane's emergency landing.
The incident came nearly three weeks after an EgyptAir flight crashed in the Mediterranean Sea as it was approaching the Egyptian coast while en route to Cairo from Paris. All 66 people on board were killed and the search for the plane's flight and data recorders - the so called black boxes - is still underway.
Last October, a Russian airliner crashed in Egypt's Sinai Peninsula shortly after taking off from the Egyptian resort city of Sharm el-Sheikh, killing all 224 people on board. A local affiliate of the extremist Islamic State group claimed responsibility for downing the aircraft just hours after the crash. In November, Russia said an explosive device brought down the aircraft.
The Russian airliner's crash has decimated Egypt's already bettered tourism industry. While the cause of the May 19 EgyptAir crash remains unknown, it has associated Egypt with another air disaster that further dented the once lucrative industry.