"We're preparing Philips for the next century," CEO Frans van Houten told a telephone press conference.
"Giving independence to our lighting solutions business will better enable it to expand its global leadership position and venture into adjacent market opportunities," Van Houten said.
"I do appreciate the magnitude of the decision we are taking, but the time is right to take the next strategic step for Philips."
Philips shares were up 3.26 per cent to 24.27 euros (USD 31.23) immediately following the announcement.
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Details on how its lighting business will be split off into a separate legal structure are to be announced in 2015.
"Both companies will be able to make the appropriate investments to boost growth and drive profitability, ultimately generating significantly more value for our customers, employees and shareholders," Philips said.
The companies will be based in the Netherlands, Van Houten said, adding that it was too early to say how many job losses might be involved.
The new structure should result in savings of 100 million euros in 2015 and another 200 million in 2016.
The move will also incur annual restructuring costs of around 50 million euros up to 2016, the company said.
The split comes after German engineering and technology giant Siemens in July last year separated the activities of its lighting company Osram, the world's second largest.
Osram, with about 40,000 staff worldwide, restructured after suffering a net loss of 378 million euros in 2012.
Philips, a household name around the world for home appliances, already has in recent years stripped down its business to focus more on advanced lighting technology and on medical technology where margins are strong and less vulnerable to competition from emerging markets.