Eighteen films were screened in the feature competition.
"Embrace of the Serpent" revolves around Karamakate, an Amazonian shaman and the last survivor of his people and two scientists who, over the course of 40 years, build a friendship, said the Hollywood Reporter.
The movie was inspired by the journals of two explorers who traveled through the Colombian Amazon during the last century: the German Theodor Koch-Grunberg and the American Richard Evans Schultes.
The SACD Prize, awarded to a French-language film, went to "My Golden Days". The film is a prequel to Arnaud Desplechin's 1996 movie "My Sex Life... Or How I Got Into an Argument".
The top awards of the festival will be handed over to the winners in a ceremony tomorrow night during the closing ceremony of the festival.