The 29-year-old actress will appear in a recurring role during the Showtime drama's third season, according to The Hollywood Reporter.
She will play a young woman named Nora, who is the neighbour of Bill and Libby Masters.
She becomes involved in Masters's research when she volunteers to become a sex surrogate.
Following her exit from "The Walking Dead", Kinney guest starred on "The Flash" as DC Comics villain Bug-Eyed Bandit.
Josh Charles, Maggie Grace, Julie Ann Emery, Tate Donovan and Sarah Silverman have also signed up to appear in "Masters of Sex" this season.